SCHEMBL5488305

SCHEMBL5488305

Oc1ccc(Cc2ccc(O)cc2)cc1.Oc1ccc(Oc2ccc(O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.70
ESR2 Q92731 3/20 0.70
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
LTA4H P09960 7/20 0.58
NR1H2 P55055 1/20 0.58
BAX Q07812 1/20 0.58
PTPN1 P18031 1/20 0.55
SRD5A2 P31213 1/20 0.52
PARP10 Q53GL7 1/20 0.48
CALM1 P0DP23 1/20 0.47
APP P05067 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12804905 1.00 ESR1 (0.70) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL14421265 1.00 ESR1 (0.70) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL17737064 0.88 ESR1 (0.67) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL11027481 0.86 LTA4H (0.61) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL12804316 0.85 ESR1 (0.70) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL26646684 0.84 GAA (0.58) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL7811939 0.84 ESR2 (1.00) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL249169 0.84 ESR2 (1.00) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL3175106 0.84 ESR2 (1.00) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL18198 0.84 ESR2 (1.00) ESR1ESR2MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817632-A1 THERMALLY DEVELOPABLE MATERIALS WITH IMPROVED CONDUCTIVE LAYER EASTMAN KODAK COMPANY (US) 2007-08-15 EP disclosed
WO-2006049866-A1 THERMALLY DEVELOPABLE MATERIALS WITH IMPROVED CONDUCTIVE LAYER EASTMAN KODAK COMPANY (US) 2006-05-11 WO disclosed
US-4358569-A FLAME RESISTANT THERMOPLASTIC MOLDING MATERIAL OF GOOD IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US disclosed