Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432886 | 0.83 | MMP8 (0.45) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL1695960 | 0.81 | KEAP1 (0.53) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL3407961 | 0.81 | ALOX5 (0.45) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL4398618 | 0.80 | ALOX5 (0.41) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL6032863 | 0.80 | ALOX5 (0.44) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL25358790 | 0.80 | MME (0.43) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL17724568 | 0.80 | ALOX5 (0.41) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28191013 | 0.80 | MMP8 (0.43) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL3173895 | 0.80 | ALOX5 (0.41) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL28746590 | 0.80 | ALOX5 (0.41) | RORCALOX5SMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2891655-A1 | Anilides-alkylthioethers as ACAT inhibitors for the treatment de dermatological diseases | PIERRE FABRE MEDICAMENT (FR) | 2015-07-08 | — | — | EP | disclosed |
| EP-2694477-A1 | ANILIDE-ALKYL THIOETHERS AS ACAT INHIBITORS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES | Pierre Fabre Medicament (FR) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012136711-A1 | ANILIDE-ALKYL THIOETHERS AS ACAT INHIBITORS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES | PIERRE FABRE MEDICAMENT (FR) | 2012-10-11 | — | — | WO | disclosed |
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |