SCHEMBL11027796

SCHEMBL11027796

CC(C)C(C(=O)O)c1occ2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.37
PPARG P37231 4/20 0.37
PPARA Q07869 4/20 0.37
AKR1B1 P15121 2/20 0.36
AKR1C3 P42330 2/20 0.36
AKR1C2 P52895 2/20 0.36
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
SMPD2 O60906 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11195352 0.83 AKR1B1 (0.44) CYP2D6PPARGPPARAAKR1B1AKR1C3
SCHEMBL2961435 0.75 UGT2B7 (0.38) KDM4EMEN1ALDH1A1HPGDKMT2A
SCHEMBL15780712 0.75 CYP2A6 (0.35) KDM4EALDH1A1HPGDLMNACYP1A2
SCHEMBL4413662 0.72 CTSD (0.38) KDM4EMEN1ALDH1A1KMT2ALMNA
SCHEMBL3983731 0.72 SLC6A2 (0.37) CYP2D6ALDH1A1HPGDHSD17B10
SCHEMBL5511628 0.71 ALDH1A1 (0.46) PPARGPPARAALDH1A1HPGDLMNA
SCHEMBL10368237 0.71 MAPT (0.35) KDM4EMEN1KMT2ALMNACYP1A2
SCHEMBL6776516 0.70 HPGD (0.41) KDM4EMEN1ALDH1A1HPGDKMT2A
SCHEMBL6207194 0.70 ALDH1A1 (0.41) AKR1B1ALDH1A1LMNANR4A2HSD17B10
SCHEMBL27666074 0.69 GPR84 (0.32) ALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431650-A INSECTICIDES; MITICIDES; PESTICIDES UNION CARBIDE CORPORATION (US) 1984-02-14 US disclosed