Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11431747 | 0.99 | ADRB2 (0.56) | CYP1A2ADRB2TSHRADRB1MAPK1 | |
| SCHEMBL11027641 | 0.86 | NLRP3 (0.46) | CYP1A2ADRB2TSHRADRB1MAPK1 | |
| SCHEMBL16794796 | 0.83 | NLRP3 (0.52) | CYP1A2NLRP3CYP2C19CYP2C9KDM4E | |
| SCHEMBL4430153 | 0.81 | ADRB3 (0.59) | CYP1A2ADRB2TSHRADRB1MAPK1 | |
| SCHEMBL10659631 | 0.80 | TSHR (0.69) | CYP1A2ADRB2TSHRADRB1MAPK1 | |
| SCHEMBL404869 | 0.78 | CYP1A2 (0.67) | CYP1A2TSHRNLRP3CYP2C19CYP2C9 | |
| SCHEMBL10711662 | 0.76 | NLRP3 (0.56) | CYP1A2NLRP3CYP2C19CYP2C9KDM4E | |
| SCHEMBL5972201 | 0.76 | NLRP3 (0.56) | CYP1A2MAPK1NLRP3CYP2C19CYP2C9 | |
| SCHEMBL27729156 | 0.75 | NLRP3 (0.46) | CYP1A2NLRP3CYP2C19CYP2C9KDM4E | |
| SCHEMBL22988070 | 0.74 | NLRP3 (0.55) | CYP1A2MAPK1CYP3A4NLRP3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057900-B1 | ANIMAL FEED ADDITIVE FOR IMPROVING GROWTH | Dr. Karl Thomae GmbH (DE) | 1985-05-08 | — | — | EP | claimed |
| US-4214001-A | ANALGESICS, ANTISPASMODICS AND ANTIASTHMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | claimed |
| EP-0057900-B1 | ANIMAL FEED ADDITIVE FOR IMPROVING GROWTH | Dr. Karl Thomae GmbH (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0057900-A1 | Animal feed additive for improving growth | Dr. Karl Thomae GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0057900-A1 | Animal feed additive for improving growth | Dr. Karl Thomae GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0008715-B1 | PHENYLETHANOLAMINES FOR USE IN COMBATTING INFLAMMATORY CONDITIONS | Dr. Karl Thomae GmbH (DE) | 1981-11-25 | — | — | EP | disclosed |
| US-4244967-A | ANTIIFLAMMATORY AND ANTIRHEUMATIC PROPERTIES | BOEHRINGER INGELHEIM GMBH (DE) | 1981-01-13 | — | — | US | disclosed |
| US-4214001-A | ANALGESICS, ANTISPASMODICS AND ANTIASTHMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | disclosed |
| EP-0008715-A1 | Phenylethanolamines for use in combatting inflammatory conditions | Dr. Karl Thomae GmbH (DE) | 1980-03-19 | — | — | EP | disclosed |