Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028018 | 0.86 | CYP1A2 (0.57) | NLRP3CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11431747 | 0.85 | ADRB2 (0.56) | NLRP3CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11030322 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ADRB2 | |
| SCHEMBL11308013 | 0.83 | ADRB2 (0.43) | CYP1A2CYP2C9SMN1; SMN2ADRB2TSHR | |
| Hydrochloric Acid SCHEMBL11052467 | 0.82 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ADRB2 | |
| SCHEMBL29798791 | 0.81 | LMNA (0.40) | CYP2C9CYP2C19SMN1; SMN2ADRB2TSHR | |
| SCHEMBL158695 | 0.81 | LMNA (0.40) | CYP2C9CYP2C19SMN1; SMN2ADRB2TSHR | |
| SCHEMBL16794796 | 0.80 | NLRP3 (0.52) | NLRP3CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10920721 | 0.80 | ADRB2 (0.47) | CYP1A2CYP2C9ADRB2TSHRADRB1 | |
| Hydrochloric Acid SCHEMBL8886084 | 0.80 | LMNA (0.39) | CYP2C9CYP2C19SMN1; SMN2ADRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057900-B1 | ANIMAL FEED ADDITIVE FOR IMPROVING GROWTH | Dr. Karl Thomae GmbH (DE) | 1985-05-08 | — | — | EP | claimed |
| US-4214001-A | ANALGESICS, ANTISPASMODICS AND ANTIASTHMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | claimed |
| EP-0057900-B1 | ANIMAL FEED ADDITIVE FOR IMPROVING GROWTH | Dr. Karl Thomae GmbH (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0057900-A1 | Animal feed additive for improving growth | Dr. Karl Thomae GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0057900-A1 | Animal feed additive for improving growth | Dr. Karl Thomae GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0008715-B1 | PHENYLETHANOLAMINES FOR USE IN COMBATTING INFLAMMATORY CONDITIONS | Dr. Karl Thomae GmbH (DE) | 1981-11-25 | — | — | EP | disclosed |
| US-4244967-A | ANTIIFLAMMATORY AND ANTIRHEUMATIC PROPERTIES | BOEHRINGER INGELHEIM GMBH (DE) | 1981-01-13 | — | — | US | disclosed |
| EP-0008715-A1 | Phenylethanolamines for use in combatting inflammatory conditions | Dr. Karl Thomae GmbH (DE) | 1980-03-19 | — | — | EP | disclosed |