SCHEMBL11028041

SCHEMBL11028041

CCC(OC(=O)CCC(=O)OC(CC)[Si](OC)(OC)OC)[Si](OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
LMNA P02545 4/20 0.34
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6271670 0.92 ALDH1A1 (0.41) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL8839316 0.89 LMNA (0.46) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL8839156 0.88 MEN1 (0.33) ALDH1A1
SCHEMBL7074557 0.86
SCHEMBL8839454 0.86 LMNA (0.56) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL6559391 0.86 LMNA (0.56) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL8839357 0.86 LMNA (0.56) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL8839277 0.86 LMNA (0.56) TSHRLMNAMAPTMAPK1ALDH1A1
SCHEMBL9095088 0.84 KDM4E (0.31) LMNA
SCHEMBL4258621 0.84 TRPA1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044891-B1 PAINTABLE AND VULCANIZABLE SILICONE RUBBER, PROCESS FOR ITS MANUFACTURE AND PAINTED LAMINATE STRUCTURE GENERAL ELECTRIC COMPANY (US) 1985-06-05 EP disclosed