SCHEMBL11028060

SCHEMBL11028060

C1CCN2CCCC2=NC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.78
USP2 O75604 3/20 0.78
SIGMAR1 Q99720 1/20 0.35
NOS3 P29474 4/20 0.33
NOS1 P29475 4/20 0.33
NOS2 P35228 4/20 0.33
ACHE P22303 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
BCHE P06276 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HRH1 P35367 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3273500 0.98 INMT (0.83) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL2965377 0.98 INMT (0.83) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL2965374 0.98 INMT (0.83) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL10058697 0.95 INMT (0.86) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL2742282 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL2956216 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL219036 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL5475300 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL20718625 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1
SCHEMBL3270217 0.93 INMT (0.91) INMTUSP2SIGMAR1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0075174-B1 PROCESS FOR THE PREPARATION OF 4-NITRODIPHENYL AMINES BAYER AG (DE) 1985-08-07 EP claimed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US claimed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP claimed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP disclosed
EP-0022519-B1 PROCESS FOR THE PREPARATION OF A MIXTURE OF 2-HYDROXY AND 4-HYDROXY BENZYL ALCOHOL BAYER AG (DE) 1982-02-03 EP disclosed
EP-0022519-A1 Process for the preparation of a mixture of 2-hydroxy and 4-hydroxy benzyl alcohol BAYER AG (DE) 1981-01-21 EP disclosed
US-4245126-A FROM PHENOL AND PARAFORMALDEHYDE IN THE PRESENCE OF A CATALYST CONTAINING TWO OR MORE TERTIARY AMINES BAYER AKTIENGESELLSCHAFT (DE) 1981-01-13 US disclosed