SCHEMBL11028068

SCHEMBL11028068

CC(C)COC(=O)[C@H](CC(C)C)NC=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
DAGLA Q9Y4D2 3/20 0.38
DAGLB Q8NCG7 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NR1I2 O75469 1/20 0.38
ABHD16A O95870 1/20 0.38
LPL P06858 1/20 0.38
LIPC P11150 1/20 0.38
PNLIP P16233 1/20 0.38
CNR1 P21554 1/20 0.38
ACHE P22303 1/20 0.38
FASN P49327 1/20 0.38
PLA2G7 Q13093 1/20 0.38
ABHD12 Q8N2K0 1/20 0.38
ABHD6 Q9BV23 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3185998 0.85 PPID (0.43) TSHRDAGLADAGLBMAPTMEN1
SCHEMBL8609825 0.85 TAS1R3 (0.45)
SCHEMBL8269519 0.85 TAS1R3 (0.45)
SCHEMBL11026293 0.80 ADH1B (0.42) TSHRDAGLADAGLBMAPTMEN1
SCHEMBL13925615 0.79 NPSR1 (0.45) DAGLADAGLBMAPTMEN1KMT2A
SCHEMBL11027872 0.79 TSHR (0.45) TSHRDAGLAMAPTCNR1KDM4E
SCHEMBL11024045 0.78 CYP2C9 (0.39) TSHRKDM4EUSP2TDP1ALDH1A1
SCHEMBL29159303 0.78 DAGLA (0.47) DAGLADAGLBMAPTMEN1KMT2A
SCHEMBL29159314 0.77 DAGLA (0.46) DAGLADAGLBMAPTMEN1KMT2A
SCHEMBL13210078 0.76 ALDH1A1 (0.55) MAPTMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0080119-B1 PROCESS FOR THE PREPARATION OF N-FORMYL-ALPHA-AMINO-ACID ESTERS BASF Aktiengesellschaft (DE) 1985-06-19 EP disclosed
EP-0080119-A1 Process for the preparation of N-formyl-alpha-amino-acid esters BASF Aktiengesellschaft (DE) 1983-06-01 EP disclosed