Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | PTPRC | P08575 | 3/20 | 0.59 |
| ▸ | S100A4 | P26447 | 2/20 | 0.59 |
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | BAX | Q07812 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465035 | 0.87 | GPR35 (0.60) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| 4-Nitrocatechol SCHEMBL1608536 | 0.86 | TSHR (0.69) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| 4-Nitrocatechol SCHEMBL156909 | 0.86 | TSHR (0.69) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| 4-Nitrocatechol SCHEMBL11765698 | 0.86 | TSHR (0.69) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL8382506 | 0.84 | POLB (0.64) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| 4-Nitrocatechol SCHEMBL28290085 | 0.84 | ALDH1A1 (0.67) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| 4-Nitrocatechol SCHEMBL4071135 | 0.84 | ALDH1A1 (0.67) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL10603975 | 0.84 | ALDH1A1 (0.67) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL11309698 | 0.84 | ALDH1A1 (0.67) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL1040777 | 0.82 | GPR35 (1.00) | GPR35ALDH1A1TSHRHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153642-A2 | Process for the preparation of monomeric aromatic hydroxyurethanes | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |