Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GYS1 | P13807 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | S100A4 | P26447 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382506 | 0.89 | POLB (0.64) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL6068096 | 0.89 | LMNA (0.56) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL11028069 | 0.87 | GPR35 (0.69) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL5684890 | 0.87 | ALDH1A1 (0.59) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL9701536 | 0.86 | GPR35 (0.58) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL1539358 | 0.82 | IKBKB (0.56) | ALDH1A1HPGDMAPK1GAAGYS1 | |
| SCHEMBL12952842 | 0.81 | KMT2A (0.50) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL28239062 | 0.81 | IKBKB (0.54) | ALDH1A1HPGDMAPK1GAAGYS1 | |
| SCHEMBL1554414 | 0.80 | GPR35 (0.51) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL28592473 | 0.80 | LMNA (0.55) | GPR35ALDH1A1TP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641832-B1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0628590-B1 | Polyimide having organopolysiloxane side chain | DOW CORNING (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5527862-A | COMPATIBLE BLENDS; REINFORCED CURED COMPOSITES; HIGH STRENGTH | DOW CORNING ASIA, LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5473041-A | Increased solubility and low melting points; separation films; diaminobiphenyl-modified polysiloxanes | DOW CORNING CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0641832-A1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0628590-A2 | Polyimide having organopolysiloxane side chain | DOW CORNING CORPORATION (US) | 1994-12-14 | — | — | EP | disclosed |