Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30097789 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TNNC1MGLLPTPN1CYP1A2 | |
| SCHEMBL27690321 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TNNC1MGLLPTPN1CYP1A2 | |
| SCHEMBL27690323 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TNNC1MGLLPTPN1CYP1A2 | |
| SCHEMBL30097911 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TNNC1MGLLPTPN1CYP1A2 | |
| Benzoic Acid SCHEMBL23495906 | 0.91 | TSHR (0.50) | ALDH1A1TNNC1MGLLCYP1A2CYP2C9 | |
| Methyl Benzoate SCHEMBL23495904 | 0.91 | TSHR (0.50) | ALDH1A1TNNC1MGLLCYP1A2CYP2C9 | |
| SCHEMBL18105893 | 0.88 | CYP4A11 (0.55) | ALDH1A1PTPN1LMNANPC1MAPT | |
| SCHEMBL6705618 | 0.88 | ALDH1A1 (0.56) | ALDH1A1PTPN1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6705621 | 0.88 | ALDH1A1 (0.56) | ALDH1A1PTPN1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2002882 | 0.87 | TNNC1 (0.49) | ALDH1A1TNNC1CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673882-B2 | Inhibitors of autotaxin | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120190650-A1 | Inhibitors of Autotaxin | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190650-A1 | Inhibitors of Autotaxin | ENPP2, PHPT1, PSPH | ALDH1A1 4863/4885TNNC1 968/4885MGLL 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.