Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023164 | 0.92 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11024867 | 0.88 | MAPT (0.35) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11024373 | 0.84 | THRB (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11027208 | 0.82 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL31373822 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11026876 | 0.81 | ALDH1A1 (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22195129 | 0.79 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11025170 | 0.79 | THRB (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11024955 | 0.79 | THRB (0.41) | TSHRALDH1A1THRBHPGDFBP1 | |
| SCHEMBL11022933 | 0.78 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |