SCHEMBL11028322

SCHEMBL11028322

CCCCC(C)CCCCN

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
TSHR P16473 1/20 0.52
EPHX1 P07099 1/20 0.52
OPRM1 P35372 1/20 0.46
LMNA P02545 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
SPHK1 Q9NYA1 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
CYP3A4 P08684 1/20 0.41
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
DPP7 Q9UHL4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20710063 0.97 DNM1 (0.57) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL3626123 0.97 DNM1 (0.57) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL19103054 0.97 DNM1 (0.57) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL3624962 0.97 DNM1 (0.57) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL3626321 0.95 DNM1 (0.60) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL24107253 0.92 DNM1 (0.65) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL20017999 0.92 DNM1 (0.65) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL3620472 0.92 DNM1 (0.65) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL3622910 0.92 DNM1 (0.65) DNM1ALDH1A1MEN1KMT2ATSHR
SCHEMBL1688008 0.92 DNM1 (0.65) DNM1ALDH1A1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12246000-B2 Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides VILNIUS UNIVERSITY (LT) 2025-03-11 US disclosed
WO-2024015340-A1 CEREBLON LIGANDS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-01-18 WO disclosed
US-20240000736-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES VILNIUS UNIVERSITY (LT) 2024-01-04 US disclosed
EP-4299062-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES Vilnius University (LT) 2024-01-03 EP disclosed
WO-2023183607-A1 CEREBLON LIGANDS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-09-28 WO disclosed
US-11124498-B2 Compositions and methods for modulating protease activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-21 US disclosed
EP-3397615-B1 MIXED DECYL MERCAPTANS COMPOSITIONS AND METHODS OF MAKING SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-08-18 EP disclosed
US-20210202360-A1 SEMICONDUCTOR PACKAGE DEVICE WITH INTEGRATED INDUCTOR AND MANUFACTURING METHOD THEREOF TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD. (TW) 2021-07-01 US disclosed
WO-2020206034-A1 CELL CYCLE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS G1 THERAPEUTICS, INC. (US) 2020-10-08 WO disclosed
US-20200048227-A1 COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-02-13 US disclosed
CN-105273724-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-07-14 CN disclosed
CN-106947499-A Liquid crystal alignment agent and application thereof 奇美实业股份有限公司 2017-07-14 CN disclosed
CN-106497576-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-03-15 CN disclosed
CN-101576687-B Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHI MEI IND CO LTD 2011-07-20 CN disclosed
CN-101614912-B Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP 2011-01-05 CN disclosed
CN-101614912-A Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP 2009-12-30 CN disclosed
CN-101576687-A Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP (CN) 2009-11-11 CN disclosed
US-20080125552-A1 Low-Viscosity Microcapsule Dispersions BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) 2008-05-29 US disclosed
US-20080103265-A1 Microcapsule Dispersions BASF AKTIENGESELLSCHAFT (DE) 2008-05-01 US disclosed
EP-0106138-B1 CONTINUOUS PROCESS FOR THE HOT PHOSGENATION OF AMINES HÜLS AKTIENGESELLSCHAFT (DE) 1985-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000736-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES APP, APBA1, IAPP DNM1 1983/4885ALDH1A1 3244/4885MEN1 1754/4885
US-11124498-B2 Compositions and methods for modulating protease activity RNASE1, ADAM8, CTRL DNM1 1576/4885ALDH1A1 3631/4885MEN1 3690/4885
US-20200048227-A1 COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY RNASE1, ADAM8, CTRL DNM1 1576/4885ALDH1A1 3631/4885MEN1 3690/4885
US-12246000-B2 Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides APP, APBA1, IAPP DNM1 1983/4885ALDH1A1 3244/4885MEN1 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.