Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029084 | 0.86 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1CASP3 | |
| SCHEMBL11027043 | 0.81 | RAB9A (0.60) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7604406 | 0.80 | NPC1 (0.52) | NPC1RAB9AKMT2AMEN1CASP3 | |
| SCHEMBL15094124 | 0.79 | CA12 (0.74) | NPC1RAB9AKMT2AMEN1CASP3 | |
| SCHEMBL11027139 | 0.78 | ROCK2 (0.55) | NPC1RAB9AKMT2AMEN1CA12 | |
| SCHEMBL9428324 | 0.78 | CNR1 (0.69) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL11029559 | 0.78 | KMT2A (0.57) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL11026185 | 0.77 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1CA12 | |
| SCHEMBL11060468 | 0.77 | RAB9A (0.59) | NPC1RAB9AKMT2AMEN1ROCK2 | |
| SCHEMBL4107205 | 0.76 | TRPV1 (0.72) | NPC1RAB9AKMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |