Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027043 | 0.88 | RAB9A (0.60) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11027139 | 0.85 | ROCK2 (0.55) | KMT2AMEN1RAB9ANPC1HTT | |
| SCHEMBL9428324 | 0.85 | CNR1 (0.69) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11030224 | 0.83 | KMT2A (0.59) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11025356 | 0.82 | MTOR (0.62) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL5641191 | 0.82 | DNMT3B (0.58) | KMT2AMEN1HTTSMN1; SMN2ROCK2 | |
| SCHEMBL11060468 | 0.81 | RAB9A (0.59) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11026185 | 0.81 | NPC1 (0.57) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11028729 | 0.78 | NPC1 (0.52) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL27942206 | 0.76 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |