Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381614 | 0.82 | KCNK3 (0.43) | IRAK4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7726674 | 0.79 | MAOB (0.59) | IRAK4HTTALOX15PDE4APDE4B | |
| SCHEMBL19433124 | 0.79 | CA12 (0.47) | ALOX15ALOX12CSNK2A1RORC | |
| SCHEMBL9647072 | 0.77 | PARP10 (0.50) | IRAK4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12697239 | 0.77 | IDO1 (0.51) | IDO1TDO2ALOX15ALOX12ALDH1A1 | |
| SCHEMBL28146640 | 0.77 | TRPA1 (0.48) | IRAK4IDO1TDO2ALOX15ALOX12 | |
| SCHEMBL4962026 | 0.77 | ALDH1A1 (0.48) | IRAK4PARP10ALDH1A1RORC | |
| SCHEMBL13963701 | 0.77 | PDE10A (0.48) | IRAK4HTTALOX15ALOX12STK17B | |
| Ethane SCHEMBL27558946 | 0.76 | HTR2A (0.40) | — | |
| SCHEMBL2975257 | 0.75 | TSHR (0.47) | IRAK4ALOX15ALOX12ALDH1A1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065720-B1 | PROCESS FOR PREPARING HYDROXYPHENYL AMINE DERIVATIVES | CASSELLA Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |
| EP-0065720-A1 | Process for preparing hydroxyphenyl amine derivatives | CASSELLA Aktiengesellschaft (DE) | 1982-12-01 | — | — | EP | disclosed |