Sugi Predict

Sugi Predict / Compounds / SCHEMBL1102902

SCHEMBL1102902

SCHEMBL1102902

C[Si]1(C)c2ccccc2N(c2c3ccccc3c(N3c4ccccc4[Si](C)(C)c4ccccc43)c3ncccc23)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 6/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ PAX8 Q06710 1/20 0.35
▸ KDM4E B2RXH2 7/20 0.35
▸ HTT P42858 5/20 0.34
▸ SLC6A2 P23975 1/20 0.34
▸ TP53 P04637 3/20 0.34
▸ USP2 O75604 2/20 0.34
▸ ALOX15 P16050 2/20 0.34
▸ NFKB1 P19838 2/20 0.34
▸ NFKB2 Q00653 2/20 0.34
▸ RELA Q04206 2/20 0.34
▸ MAPT P10636 4/20 0.33
▸ LMNA P02545 3/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ ALOX12 P18054 2/20 0.33
▸ KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103092 0.88 PAX8 (0.32) L3MBTL1NPC1HSP90AA1PAX8KDM4E
SCHEMBL1103018 0.83 KDM4E (0.34) L3MBTL1NPC1HSP90AA1PAX8KDM4E
SCHEMBL1103239 0.83 GAA (0.34) KDM4EHTTMAPTALDH1A1POLB
SCHEMBL1103177 0.81 AKT1 (0.33) L3MBTL1KDM4EMAPTLMNAALDH1A1
SCHEMBL1103025 0.80 KDM4E (0.37) L3MBTL1NPC1HSP90AA1PAX8KDM4E
SCHEMBL1102739 0.78 MAOA (0.33) NPC1KDM4EHTTTP53NFKB1
SCHEMBL1102977 0.77 HTT (0.38) L3MBTL1NPC1HSP90AA1KDM4EHTT
SCHEMBL1102903 0.77 KDM4E (0.43) L3MBTL1NPC1HSP90AA1KDM4EHTT
SCHEMBL1102797 0.77 HTT (0.38) L3MBTL1NPC1HSP90AA1PAX8KDM4E
SCHEMBL1102807 0.77 HSP90AA1 (0.36) L3MBTL1NPC1HSP90AA1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 — — US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 — — US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 — — US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 — — US disclosed
EP-2147962-A1 Azaanthracene-derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 L3MBTL1 1629/4885NPC1 1582/4885HSP90AA1 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.