SCHEMBL1103092

SCHEMBL1103092

C[Si]1(C)c2ccccc2N(c2c3ccccc3c(-c3ccccc3)c3ncccc23)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CKS1B P61024 1/20 0.32
GLO1 Q04760 1/20 0.32
SKP2 Q13309 1/20 0.32
HTT P42858 4/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KMT2A Q03164 3/20 0.31
USP2 O75604 2/20 0.31
TP53 P04637 2/20 0.31
MEN1 O00255 2/20 0.31
ALOX15 P16050 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102902 0.88 L3MBTL1 (0.36) PAX8L3MBTL1NPC1HSP90AA1GLO1
SCHEMBL1103177 0.87 AKT1 (0.33) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL1103239 0.84 GAA (0.34) HTTALDH1A1KDM4EHSD17B10POLB
SCHEMBL1103075 0.82 MAPT (0.39) L3MBTL1HTTALDH1A1KDM4EHSD17B10
SCHEMBL1103064 0.81 ALDH1A1 (0.33) L3MBTL1NPC1HSP90AA1CKS1BGLO1
SCHEMBL16314424 0.81 LMNA (0.32) L3MBTL1NPC1HSP90AA1CKS1BGLO1
SCHEMBL1103070 0.81 KMT2A (0.36) HTTALDH1A1HSD17B10KMT2AMEN1
SCHEMBL1103072 0.81 HTT (0.33) L3MBTL1HTTALDH1A1KDM4EHSD17B10
SCHEMBL1102773 0.80 ALOX5 (0.33)
SCHEMBL1103032 0.78 PDE4A (0.31) PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 PAX8 1294/4885L3MBTL1 1629/4885NPC1 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.