Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598520 | 0.81 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7487285 | 0.81 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11025263 | 0.81 | HDAC6 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11029166 | 0.81 | HDAC6 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5694343 | 0.80 | MEN1 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8595899 | 0.78 | TDP1 (0.74) | MEN1KMT2AMAPK14TDP1 | |
| SCHEMBL11028825 | 0.77 | KDM4E (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11025646 | 0.77 | ALDH1A1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10099565 | 0.76 | CYP1A2 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11021806 | 0.75 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4409240-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS, BRONCHODILATOR, AND ANTIARTHRITIC AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | disclosed |