Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598520 | 1.00 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2303341 | 0.92 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21450578 | 0.89 | SMN1; SMN2 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Benzoic Acid SCHEMBL28285625 | 0.87 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11518102 | 0.85 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8391563 | 0.85 | SMN1; SMN2 (0.73) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8393362 | 0.85 | SMN1; SMN2 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10099565 | 0.84 | CYP1A2 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10099589 | 0.84 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25123079 | 0.83 | SMN1; SMN2 (0.76) | HDAC3HDAC6SMN1; SMN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080334-B1 | 4-(N-(HYDROXYBENZYL)AMINOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACIDS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | claimed |
| EP-0080334-A1 | 4-(N-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-06-01 | — | — | EP | claimed |
| US-RE30149-E | OXIDATION OF 4-AMINOMETHYL-CYCLOHEXANE METHANOL | AB KABI (SE) | 1979-11-13 | — | — | US | claimed |
| US-8093227-B2 | Monosaccharide compounds and methods therefor | ALCHEMIA PTY LTD (AU) | 2012-01-10 | — | — | US | disclosed |
| US-8093227-B2 | Monosaccharide compounds and methods therefor | ALCHEMIA PTY LTD (AU) | 2012-01-10 | — | — | US | disclosed |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | ALCHEMIA PTY LTD. (AU) | 2010-07-22 | — | — | US | disclosed |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | ALCHEMIA PTY LTD. (AU) | 2010-07-22 | — | — | US | disclosed |
| US-7582280-B2 | Conjugates of antioxidants with metal chelating ligands for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2009-09-01 | — | — | US | disclosed |
| US-20080274048-A1 | CONJUGATES OF ANTIOXIDANTS WITH METAL CHELATING LIGANDS FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2008-11-06 | — | — | US | disclosed |
| US-7417129-B2 | Combinatorial libraries of monosaccharides | ALCHEMIA PTY LTD (AU) | 2008-08-26 | — | — | US | disclosed |
| US-7417129-B2 | Combinatorial libraries of monosaccharides | ALCHEMIA PTY LTD (AU) | 2008-08-26 | — | — | US | disclosed |
| US-7160535-B2 | Conjugates of antioxidants with metal chelating ligands for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL BV (NL) | 2007-01-09 | — | — | US | disclosed |
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0080334-B1 | 4-(N-(HYDROXYBENZYL)AMINOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACIDS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4464396-A | 4-[N-(Hydroxybenzyl)aminomethyl]cyclohexane-1-carboxylic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0080334-A1 | 4-(N-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-06-01 | — | — | EP | disclosed |
| US-RE30149-E | OXIDATION OF 4-AMINOMETHYL-CYCLOHEXANE METHANOL | AB KABI (SE) | 1979-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274048-A1 | CONJUGATES OF ANTIOXIDANTS WITH METAL CHELATING LIGANDS FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SOD3, CAT, SOD1 | HDAC3 799/4885HDAC4 2765/4885HDAC1 1438/4885 |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | SLC5A1, UGGT1, MRPL21 | HDAC3 2450/4885HDAC4 1649/4885HDAC1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.