Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319869 | 0.98 | KDM4E (0.33) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4352034 | 0.90 | ALDH1A1 (0.34) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3060057 | 0.87 | KDM4E (0.33) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6943640 | 0.87 | KDM4E (0.33) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3655351 | 0.87 | KDM4E (0.33) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11141982 | 0.85 | OPRK1 (0.33) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL213436 | 0.84 | ALDH1A1 (0.35) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL147492 | 0.79 | KDM4E (0.36) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2699253 | 0.79 | ALDH1A1 (0.35) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6527091 | 0.76 | OPRK1 (0.35) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069622-B1 | PROCESS FOR THE PREPARATION OF BETA-CYCLO-SUBSTITUTED ETHYL AMINES, AND PRODUCTS SO OBTAINED | SANOFI S.A. (FR) | 1985-09-18 | — | — | EP | claimed |