Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319869 | 0.92 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11029404 | 0.90 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3430768 | 0.84 | ALDH1A1 (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL147492 | 0.83 | KDM4E (0.36) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL213436 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2699253 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6943640 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6527091 | 0.80 | OPRK1 (0.35) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3655351 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3060057 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | claimed |
| WO-2008157216-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2008-12-24 | — | — | WO | claimed |
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2008157216-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-0190015-B1 | NOVEL 4H-1-BENZOPYRAN-4-ONES AND THEIR SULPHUR CONTAINING ANALOGS | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4678787-A | PSYCHOSIS, SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0190015-A1 | Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs | WARNER-LAMBERT COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | HTR6, HTR2B, HTR3B | ALDH1A1 721/4885KDM4E 2270/4885KMT2A 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.