Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11029622

C=CC(Cl)(Cc1ccccc1)C(C)(C)CCCCCC.N

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
DNM1 Q05193 2/20 0.36
MBOAT4 Q96T53 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP19A1 P11511 3/20 0.35
SLC6A2 P23975 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27490572 0.82 DNM1 (0.38) MMP1MMP9MMP13EBPSIGMAR1
Ammonia Solution, Strong SCHEMBL11273750 0.77 DNM1 (0.42) MMP1MMP9MMP13EBPSIGMAR1
Ammonia Solution, Strong SCHEMBL16427990 0.77 DNM1 (0.42) MMP1MMP9MMP13EBPSIGMAR1
Ammonia Solution, Strong SCHEMBL6060443 0.76 MMP1 (0.40) MMP1MMP9MMP13EBPSIGMAR1
SCHEMBL4378997 0.75 SLC6A2 (0.43) MMP1MMP9MMP13EBPSIGMAR1
Ammonia Solution, Strong SCHEMBL27433180 0.75 SLC6A2 (0.44) MMP1MMP9MMP13SIGMAR1DNM1
Ammonia Solution, Strong SCHEMBL27641275 0.75 SLC6A2 (0.44) MMP1MMP9MMP13SIGMAR1DNM1
SCHEMBL4374768 0.74 MMP1 (0.37) MMP1MMP9MMP13EBPSIGMAR1
Hydrochloric Acid SCHEMBL11029623 0.74 SLC6A2 (0.42) MMP1MMP9MMP13EBPSIGMAR1
Hydrochloric Acid SCHEMBL5707333 0.74 SLC6A2 (0.42) MMP1MMP9MMP13EBPSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087473-A4 QUATERNARY AMMONIUM GROUP-CONTAINING POLYMERS HAVING ANTIMICROBIAL ACTIVITY. DYPANOL SHAREHOLDERS LIQUIDATI (US) 1984-02-09 EP disclosed
EP-0087473-A1 QUATERNARY AMMONIUM GROUP-CONTAINING POLYMERS HAVING ANTIMICROBIAL ACTIVITY DYPANOL SHAREHOLDERS' LIQUIDATING TRUST (US) 1983-09-07 EP disclosed
WO-1983001002-A1 QUATERNARY AMMONIUM GROUP-CONTAINING POLYMERS HAVING ANTIMICROBIAL ACTIVITY DYNAPOL SHAREHOLDERS LIQUIDATI (US) 1983-03-31 WO disclosed