SCHEMBL11029698

SCHEMBL11029698

N#CC(Cl)Cl.c1cc2ccc1o2

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
HIF1A Q16665 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8546243 0.73 ALDH1A1 (0.60) ALDH1A1CYP3A4ALOX15HIF1A
SCHEMBL1180554 0.71
SCHEMBL28133271 0.67
SCHEMBL2005231 0.67 ALDH1A1 (0.90) ALDH1A1CYP3A4ALOX15HIF1A
Methyl Alcohol SCHEMBL28639463 0.61
Acetonitrile SCHEMBL8836994 0.61 ALDH1A1 (0.75) ALDH1A1CYP3A4ALOX15HIF1A
Chloroform SCHEMBL28563775 0.55 CA2 (0.55) ALDH1A1
SCHEMBL11340227 0.52
SCHEMBL10635939 0.50
SCHEMBL3150854 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0031938-B1 USE OF ARYLOXY(THIO)CARBOXYLIC ACID NITRILES AND AMIDOXIMES AS ANTIDOTES AGAINST HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-27 EP claimed