Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 2/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ESRRA | P11474 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967979 | 0.91 | IDO1 (0.46) | IDO1EP300KAT8NQO1IMPDH2 | |
| SCHEMBL8656155 | 0.87 | ESRRA (0.47) | MAPTESRRALMNACYP1A2CYP3A4 | |
| SCHEMBL10961278 | 0.84 | IDO1 (0.51) | IDO1EP300KAT8NQO1IMPDH2 | |
| SCHEMBL10963903 | 0.80 | ESRRA (0.45) | IDO1MAPTESRRALMNACYP1A2 | |
| SCHEMBL10998177 | 0.80 | IDO1 (0.47) | IDO1EP300KAT8NQO1IMPDH2 | |
| SCHEMBL23391525 | 0.79 | TTR (0.48) | MAPTGAADHPS | |
| SCHEMBL11029673 | 0.79 | ESRRA (0.47) | MAPTESRRACYP1A2CYP3A4HPGD | |
| SCHEMBL10965638 | 0.78 | MAPT (0.51) | IDO1MAPTRORCLMNACYP1A2 | |
| SCHEMBL5202067 | 0.77 | PDGFRA (0.57) | — | |
| SCHEMBL10962017 | 0.76 | ESRRA (0.47) | IDO1MAPTESRRALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |