Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484572 | 0.82 | ESRRA (0.56) | ESRRAHPGDSCN9AKDM1ARCOR1 | |
| SCHEMBL8656155 | 0.81 | ESRRA (0.47) | ESRRAHPGDCYP2A6CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10884537 | 0.81 | ESRRA (0.54) | ESRRAHPGDSCN9AKDM1ARCOR1 | |
| SCHEMBL11029935 | 0.79 | IDO1 (0.51) | ESRRAHPGDCYP1A2CYP3A4GAA | |
| SCHEMBL11026917 | 0.77 | ALOX5 (0.54) | ESRRAHPGDCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10988253 | 0.77 | HPGD (0.66) | ESRRAHPGDSCN9AKDM1ARCOR1 | |
| SCHEMBL9324242 | 0.77 | ALDH1A1 (0.56) | ESRRAHPGDKDM1ARCOR1HTR1B | |
| SCHEMBL7219795 | 0.76 | HPGD (0.45) | ESRRAHPGDSCN9AKDM1ARCOR1 | |
| SCHEMBL5402131 | 0.76 | HTR1B (0.48) | ESRRAHPGDCYP2A6CYP1A2HTR1B | |
| SCHEMBL11027863 | 0.75 | EGFR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |