Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030290 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11025683 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11025717 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11028130 | 0.73 | MAPT (0.60) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11028131 | 0.73 | MAPT (0.60) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL16211074 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL12127344 | 0.72 | AGTR1 (0.53) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL16211072 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11027185 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTAGTR1KMT2A | |
| SCHEMBL11027188 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTAGTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120190009-A1 | Viral Modulators and Processes Thereof | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190009-A1 | Viral Modulators and Processes Thereof | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190009-A1 | Viral Modulators and Processes Thereof | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | MAVS, HAVCR2, HDLBP | ALDH1A1 4453/4885MAPT 1778/4885HTT 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.