Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCKAR | P32238 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616185 | 1.00 | ACE (0.59) | ACEIDO1CTSSCTSLCTSB | |
| SCHEMBL8935942 | 0.88 | PPARA (0.67) | ACEIDO1CTSSCTSLCCKAR | |
| SCHEMBL10977853 | 0.86 | CTSL (0.57) | IDO1CTSSCTSLCTSKITGB3 | |
| SCHEMBL27909397 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL21473784 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL67020 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL66220 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL606309 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL795685 | 0.84 | ACE (0.79) | ACECTSSCTSLCTSBCTSK | |
| Water SCHEMBL15362013 | 0.83 | ACE (0.77) | ACECTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |