Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 2/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | CDC25B | P30305 | 4/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616185 | 0.88 | ACE (0.59) | PPARAPPARGCTSSIDO1MEN1 | |
| SCHEMBL11030896 | 0.88 | ACE (0.59) | PPARAPPARGCTSSIDO1MEN1 | |
| SCHEMBL17051 | 0.85 | PPARA (0.90) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL828674 | 0.85 | PPARA (0.90) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL1132901 | 0.85 | PPARA (0.90) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL20899650 | 0.81 | PPARA (0.82) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL12130757 | 0.81 | PPARA (0.85) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL18555201 | 0.79 | PPARA (0.78) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL18555200 | 0.79 | PPARA (0.78) | PPARAPPARGCTSSKLK7KLK5 | |
| SCHEMBL10977853 | 0.79 | CTSL (0.57) | CTSSIDO1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5531978-A | CHELATE COMPOUNDS, IMAGING | NYCOMED IMAGING AS (NO) | 1996-07-02 | — | — | US | disclosed |
| US-5419893-A | Aminopolycarboxylic acids and derivatives thereof for magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1995-05-30 | — | — | US | disclosed |
| WO-1989000557-A1 | AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1989-01-26 | — | — | WO | disclosed |