Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL11031063

C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C.OCCOCCOCCOCCO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.69
ALDH1A1 P00352 5/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP3A4 P08684 2/20 0.56
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 9/20 0.52
HSD17B10 Q99714 1/20 0.52
HPGD P15428 1/20 0.43
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.34
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17936718 0.89 THRB (0.88) THRBALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL10426882 0.88 ALDH1A1 (0.66) THRBALDH1A1TP53HIF1ACYP3A4
Propanol SCHEMBL7031961 0.86 ALDH1A1 (0.63) THRBALDH1A1TP53HIF1ACYP3A4
Alcohol SCHEMBL7030010 0.86 ALDH1A1 (0.68) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL238953 0.86 THRB (0.70) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL7642880 0.86 THRB (0.67) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL29776450 0.85 THRB (0.93) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL39816 0.84 THRB (0.74) THRBALDH1A1TP53HIF1ACYP3A4
1,6-Hexanediol SCHEMBL11572707 0.83 ALDH1A1 (0.59) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL2742409 0.83 THRB (0.97) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119219-A1 COATING COMPOSITIONS AND THEIR USE IN THE RESTORATIVE AND/OR PROTECTIVE TREATMENT OF PHOTOGRAPHIC ELEMENTS. EASTMAN KODAK CO (US) 1984-09-26 EP disclosed
WO-1984001228-A1 COATING COMPOSITIONS AND THEIR USE IN THE RESTORATIVE AND/OR PROTECTIVE TREATMENT OF PHOTOGRAPHIC ELEMENTS EASTMAN KODAK CO (US) 1984-03-29 WO disclosed