Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606314 | 0.87 | THRB (0.60) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4549061 | 0.87 | THRB (0.60) | THRBTSHRALDH1A1TP53HIF1A | |
| Tetraethylene Glycol SCHEMBL11031063 | 0.86 | THRB (0.69) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL238953 | 0.85 | THRB (0.70) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29776450 | 0.84 | THRB (0.93) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL39816 | 0.83 | THRB (0.74) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16939129 | 0.82 | THRB (0.63) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2742409 | 0.82 | THRB (0.97) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL20831280 | 0.82 | THRB (0.97) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17878009 | 0.82 | THRB (0.97) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420441-B1 | DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS | SHIPLEY COMPANY, L.L.C. | 2002-07-16 | — | — | US | claimed |