SCHEMBL11031089

SCHEMBL11031089

CC(=O)C(C)=C[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THPO P40225 1/20 0.35
MAPT P10636 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447742 0.79 PTGS1 (0.36)
SCHEMBL1679536 0.77 LMNA (0.37)
Lithium Ion SCHEMBL28788175 0.75 CA4 (0.38) CA4
SCHEMBL9156223 0.73 ALDH1A1 (0.40)
SCHEMBL7566089 0.71
SCHEMBL380120 0.65
SCHEMBL5668997 0.65
SCHEMBL18469390 0.65 TSHR (0.46) TSHRTHPOCA4
SCHEMBL380121 0.65
SCHEMBL2029340 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0114001-A1 New anthracyclinones and their production MEIJI SEIKA KAISHA LTD. (JP) 1984-07-25 EP disclosed