Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 6/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.53 |
| ▸ | KCNJ8 | Q15842 | 6/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975838 | 0.89 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7515733 | 0.84 | ABCC9 (0.68) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL15359210 | 0.83 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7515569 | 0.83 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL15359209 | 0.83 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL11031350 | 0.78 | NR1H2 (0.38) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL8409262 | 0.77 | AR (0.67) | ABCC9ABCC8KCNJ11KCNJ8AR | |
| SCHEMBL8519256 | 0.77 | AR (0.63) | ABCC9ABCC8KCNJ11KCNJ8AR | |
| SCHEMBL10421023 | 0.76 | AR (0.52) | ABCC9ABCC8KCNJ11KCNJ8AR | |
| SCHEMBL7524151 | 0.76 | AR (0.81) | ABCC9ABCC8KCNJ11KCNJ8AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002892-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-06 | — | — | EP | claimed |