Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.68 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.68 |
| ▸ | KCNJ11 | Q14654 | 8/20 | 0.68 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.68 |
| ▸ | PDK1 | Q15118 | 11/20 | 0.65 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.65 |
| ▸ | PDK3 | Q15120 | 11/20 | 0.65 |
| ▸ | PDK4 | Q16654 | 11/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15359209 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL15359210 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7515569 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7518469 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL8519769 | 0.85 | ALDH1A1 (0.54) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL11031351 | 0.84 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL8866418 | 0.83 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL10984365 | 0.82 | AR (0.54) | — | |
| SCHEMBL8866364 | 0.81 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL7523309 | 0.81 | PDK1 (0.70) | ABCC9ABCC8KCNJ11KCNJ8PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886515-B1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | OREAL (FR) | 2002-01-16 | — | — | EP | claimed |
| US-6291532-B1 | Use of N-aryl-2-hydroxyalkylamides for stimulating or inducing hair growth and/or arresting hair loss | L'OREAL (FR) | 2001-09-18 | — | — | US | claimed |
| EP-0886515-A1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | L'OREAL (FR) | 1998-12-30 | — | — | EP | claimed |
| WO-1997032562-A1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | L'OREAL (FR) | 1997-09-12 | — | — | WO | claimed |
| EP-0002892-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-06 | — | — | EP | claimed |
| US-4191775-A | ANTIANDROGENIC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-04 | — | — | US | claimed |
| EP-0002892-A1 | Amide derivatives, process for their manufacture and pharmaceutical or veterinary compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-07-11 | — | — | EP | claimed |
| EP-0886515-B1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | OREAL (FR) | 2002-01-16 | — | — | EP | disclosed |
| US-6291532-B1 | Use of N-aryl-2-hydroxyalkylamides for stimulating or inducing hair growth and/or arresting hair loss | L'OREAL (FR) | 2001-09-18 | — | — | US | disclosed |
| EP-0886515-A1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | L'OREAL (FR) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997032562-A1 | USE OF N-ARYL-2-HYDROXYALKYLAMIDES FOR STIMULATING OR INDUCING HAIR GROWTH AND/OR ARRESTING HAIR LOSS | L'OREAL (FR) | 1997-09-12 | — | — | WO | disclosed |
| EP-0002892-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-06 | — | — | EP | disclosed |
| US-4191775-A | ANTIANDROGENIC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-04 | — | — | US | disclosed |
| EP-0002892-A1 | Amide derivatives, process for their manufacture and pharmaceutical or veterinary compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-07-11 | — | — | EP | disclosed |