Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.94 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.89 |
| ▸ | APP | P05067 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526630 | 0.97 | TDP1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5097 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4376059 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL3947579 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL1827219 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL357435 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL208637 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL21840887 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methane SCHEMBL22289589 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5601373 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069622-B1 | PROCESS FOR THE PREPARATION OF BETA-CYCLO-SUBSTITUTED ETHYL AMINES, AND PRODUCTS SO OBTAINED | SANOFI S.A. (FR) | 1985-09-18 | — | — | EP | disclosed |