Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.65 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.52 |
| ▸ | CYP19A1 known ✓ | P11511 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.94 |
| ▸ | APP | P05067 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL208637 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| Hydrochloric Acid SCHEMBL1827219 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| Hydrochloric Acid SCHEMBL27958988 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| Hydrochloric Acid SCHEMBL4376059 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| SCHEMBL5097 | 0.97 | — | — | |
| SCHEMBL8526630 | 0.97 | TDP1 (1.00) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| Ethane SCHEMBL11031442 | 0.94 | TDP1 (0.94) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| SCHEMBL5601373 | 0.94 | TDP1 (0.94) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| SCHEMBL21840887 | 0.94 | TDP1 (0.94) | ALDH1A1TDP1CYP3A4MAPK1APP | |
| Methane SCHEMBL22289589 | 0.94 | TDP1 (0.94) | ALDH1A1TDP1CYP3A4MAPK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217747075-U | Anethole hydrochloride making devices | 辽宁兰得新材料科技发展有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-116421718-A | Application of humanized anti-proBDNF monoclonal antibody | 中南大学湘雅二医院 | 2023-07-14 | — | — | CN | disclosed |
| CN-217747075-U | Anethole hydrochloride making devices | 辽宁兰得新材料科技发展有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-217747075-U | Anethole hydrochloride making devices | 辽宁兰得新材料科技发展有限公司 | 2022-11-08 | — | — | CN | disclosed |
| EP-3529260-A1 | VACCINE CONSTRUCTS AND USES THEREOF AGAINST STAPHYLOCOCCUS INFECTIONS | SOCPRA - Sciences et Génie s.e.c. (CA) | 2019-08-28 | — | — | EP | disclosed |
| CN-109804306-A | Light orientation copolymer material | 罗利克技术有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-108374001-A | It improves than glucose oxidase mutant living and its encoding gene and application | 广东溢多利生物科技股份有限公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-108350363-A | Can photo-alignment material composition | 罗利克技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108350174-A | Photo-alignment material | 罗利克技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108251392-A | It improves than living and the glucose oxidase mutant of thermal stability and its encoding gene and application | 广东溢多利生物科技股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| WO-1996030037-A1 | METHOD OF TREATING CONDITIONS ASSOCIATED WITH BURN INJURIES | XOMA CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5494638-A | Support membrane | HYPOGUARD (UK) LIMITED (GB) | 1996-02-27 | — | — | US | disclosed |
| EP-0591315-A1 | SUPPORT MEDIUM. | HYPOGUARD UK LTD (GB) | 1994-04-13 | — | — | EP | disclosed |
| EP-0591322-A1 | REAGENT MIXTURES FOR GLUCOSE ASSAY | HYPOGUARD (UK) LIMITED (GB) | 1994-04-13 | — | — | EP | disclosed |
| WO-1992022669-A1 | REAGENT MIXTURES FOR GLUCOSE ASSAY | HYPOGUARD (UK) LIMITED (GB) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992022815-A1 | SUPPORT MEDIUM | HYPOGUARD (UK) LIMITED (GB) | 1992-12-23 | — | — | WO | disclosed |
| US-4988616-A | Triarylmethane indicators for hydrogen peroxide | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4894472-A | REDOX INDICATORS, DETECTION OF PEROXIDASE | MILES INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0284951-A2 | New dicyanoethylaryl derivatives, processes for their preparation and their use as redox indicators | MILES INC. (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0149168-A1 | Immunoassay | DAIICHI PURE CHEMICALS CO. LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |