Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226714 | 1.00 | LMNA (0.43) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11031941 | 1.00 | LMNA (0.43) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11153443 | 1.00 | LMNA (0.43) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11150126 | 0.91 | FABP7 (0.35) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL10881004 | 0.91 | TDP1 (0.36) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL10880995 | 0.91 | TDP1 (0.36) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL10880992 | 0.91 | TDP1 (0.36) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11253622 | 0.90 | TDP1 (0.43) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11253619 | 0.90 | TDP1 (0.43) | LMNATDP1ATMADRA2ACNR1 | |
| SCHEMBL11220706 | 0.90 | TDP1 (0.43) | LMNATDP1ATMADRA2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069761-B1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES | FMC Corporation (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4423255-A | AND PYRETHROID ESTERS | FMC CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| US-4417078-A | HYDROBORATION, HYDROXYLATION OF AN INDENE; INSECTICIDE INTERMEDIATE | FMC CORPORATION (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0069761-A4 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. | FMC CORP (US) | 1983-05-16 | — | — | EP | disclosed |
| EP-0069761-A1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. | FMC CORP (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4346251-A | 4-Substituted-2-indanols | FMC CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| WO-1982002321-A1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES | FMC CORP (US) | 1982-07-22 | — | — | WO | disclosed |
| US-4333950-A | MITICIDES | FMC CORPORATION (US) | 1982-06-08 | — | — | US | disclosed |
| US-4263319-A | CYCLOPROPYL ESTERS | FMC CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |