Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635178 | 0.87 | LMNA (0.60) | LMNAGAASMN1; SMN2TAS2R14CTNNB1 | |
| SCHEMBL31575836 | 0.87 | LMNA (0.60) | LMNAGAASMN1; SMN2TAS2R14CTNNB1 | |
| SCHEMBL10892500 | 0.87 | LMNA (0.46) | LMNAGAASMN1; SMN2TAS2R14CTNNB1 | |
| SCHEMBL23412316 | 0.83 | ALDH1A1 (0.54) | LMNAGAASMN1; SMN2TAS2R14ALDH1A1 | |
| SCHEMBL10893077 | 0.82 | ALDH1A1 (0.40) | LMNAGAASMN1; SMN2TAS2R14CTNNB1 | |
| SCHEMBL6737753 | 0.78 | ALDH1A1 (0.46) | LMNAGAAALDH1A1ALOX15PTGS1 | |
| SCHEMBL12869576 | 0.78 | AKR1C3 (0.53) | LMNAGAASMN1; SMN2ALDH1A1CES1 | |
| SCHEMBL1324384 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1ALOX15CES1CES2 | |
| SCHEMBL12869592 | 0.74 | AKR1C3 (0.42) | LMNAGAASMN1; SMN2ALDH1A1CES1 | |
| SCHEMBL4204571 | 0.72 | ALDH1A1 (0.40) | LMNAGAASMN1; SMN2ALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500471-A | REACTING TRICHLORO-OR TRIBROMOMETHYLBENZOYL HALIDES WITH HYDROGEN FLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0038223-A1 | Process for the preparation of trifluoromethylbenzoyl halides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-10-21 | — | — | EP | disclosed |