Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10807955 | 0.94 | OPRD1 (0.41) | CARM1PRMT6OPRD1HPGDHTT | |
| Fumaric Acid SCHEMBL10807962 | 0.94 | OPRD1 (0.41) | CARM1PRMT6OPRD1HPGDHTT | |
| SCHEMBL11031298 | 0.88 | RAB9A (0.52) | OPRD1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL11034086 | 0.87 | TRPA1 (0.53) | OPRD1NPC1RAB9ACTSBCTSK | |
| SCHEMBL10809255 | 0.86 | NPC1 (0.55) | OPRD1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10803800 | 0.85 | KMT2A (0.49) | HPGDHTTNPC1RAB9AMEN1 | |
| Fumaric Acid SCHEMBL10804156 | 0.85 | HPGD (0.46) | OPRD1HPGDHTTNPC1RAB9A | |
| Fumaric Acid SCHEMBL10804148 | 0.85 | HPGD (0.46) | OPRD1HPGDHTTNPC1RAB9A | |
| Fumaric Acid SCHEMBL10804717 | 0.84 | TRPA1 (0.47) | OPRD1NPC1RAB9ACTSBCTSK | |
| SCHEMBL10807044 | 0.82 | OPRD1 (0.59) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984003090-A1 | SUBSTITUTED 1-AZASPIRO AD4.5 BDDECANES AND 1-AZASPIRO AD5.5 BDUNDECANES | STRUPCZEWSKI JOSEPH T (US) | 1984-08-16 | — | — | WO | claimed |
| US-4430335-A | FORMATION FROM KETONE AND SODIUM CYANOBOROHYDRIDE | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-02-07 | — | — | US | claimed |