SCHEMBL11032150

SCHEMBL11032150

O=Cc1ccc(F)c(Oc2ccc(Oc3ccccc3)cc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.60
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 5/20 0.42
FAAH O00519 1/20 0.41
TLR4 O00206 1/20 0.41
TLR2 O60603 1/20 0.41
MAPT P10636 1/20 0.40
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 3/20 0.40
PARP10 Q53GL7 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PARP3 Q9Y6F1 1/20 0.39
ERN1 O75460 1/20 0.39
LTA4H P09960 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GSTP1 P09211 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920233 0.97 TTR (0.64) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL30508566 0.97 TTR (0.64) TTRLMNAGAAKMT2AALDH1A1
Sulfurous Acid SCHEMBL10561789 0.89 TTR (0.56) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL10891697 0.87 ALDH1A1 (0.51) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL9560357 0.85 HSD17B10 (0.48) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL9560716 0.84 TTR (0.45) TTRLMNAGAAALDH1A1MAPT
SCHEMBL13218233 0.83 TTR (0.64) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL10893523 0.83 MAOA (0.48) TTRLMNAKMT2AALDH1A1MAPT
SCHEMBL3712082 0.82 TTR (0.52) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL11795573 0.81 TTR (0.81) TTRLMNAGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59046239-A None JP disclosed
JP-59046239-A None JP disclosed
JP-S5946239-A 3-(4-PHENOXYPHENOXY)-4-FLUOROBENZALDEHYDE AND ITS PREPARATION SUMITOMO CHEM CO LTD 1984-03-15 JP disclosed
JP-S5946239-A 3-(4-PHENOXYPHENOXY)-4-FLUOROBENZALDEHYDE AND ITS PREPARATION SUMITOMO CHEM CO LTD 1984-03-15 JP disclosed