SCHEMBL920233

SCHEMBL920233

O=Cc1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.64
LMNA P02545 3/20 0.49
GAA P10253 2/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 7/20 0.43
TSHR P16473 2/20 0.42
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
MAPT P10636 1/20 0.39
CYP2A6 P11509 1/20 0.39
TRIM24 O15164 1/20 0.39
HPGD P15428 1/20 0.39
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PARP10 Q53GL7 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30508566 1.00 TTR (0.64) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL11032150 0.97 TTR (0.60) TTRLMNAGAAKMT2AALDH1A1
Sulfurous Acid SCHEMBL10561789 0.92 TTR (0.56) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL10891697 0.86 ALDH1A1 (0.51) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL13218233 0.86 TTR (0.64) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL10893523 0.85 MAOA (0.48) TTRLMNAKMT2AALDH1A1TSHR
SCHEMBL3712082 0.85 TTR (0.52) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL9560357 0.85 HSD17B10 (0.48) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL11795573 0.84 TTR (0.81) TTRLMNAGAAKMT2AALDH1A1
SCHEMBL29446607 0.84 TTR (0.81) TTRLMNAGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439937-A Synthetic method of 4-fluoro-3-phenoxybenzaldehyde serving as key intermediate of insect repellent 康龙化成(绍兴)药业有限公司 2024-08-06 CN claimed
CN-116396912-B Pyrethroid pesticide intermediate degrading bacterium, microbial inoculum and wastewater treatment method and treatment device thereof 江苏朴厚环境工程有限公司 2023-08-08 CN claimed
CN-116410070-A Production process of p-fluoro-m-phenoxy benzaldehyde 江苏优嘉植物保护有限公司 2023-07-11 CN claimed
CN-116396912-A Pyrethroid pesticide intermediate degrading bacterium, microbial inoculum and wastewater treatment method and treatment device thereof 江苏朴厚环境工程有限公司 2023-07-07 CN claimed
EP-2186794-B1 MONOHALOGENATED PYRETHRIC ACID ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL ESTER AND ITS PREPARATION METHOD AND USE UNIV EAST CHINA NORMAL (CN) 2014-11-26 EP claimed
US-8202904-B2 α-cyano-4-fluoro-3-phenoxybenzyl meta-halo pyrethrate, a process for preparing the same and the uses thereof EAST CHINA NORMAL UNIVERSITY (CN) 2012-06-19 US claimed
US-20100286265-A1 ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL META-HALO PYRETHRATE, A PROCESS FOR PREPARING THE SAME AND THE USES THEREOF EAST CHINA NORMAL UNIVERSITY (CN) 2010-11-11 US claimed
WO-2010086876-A2 ETHER SYNTHESIS ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) 2010-08-05 WO claimed
EP-2186794-A1 MONOHALOGENATED PYRETHRIC ACID ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL ESTER AND ITS PREPARATION METHOD AND USE East China Normal University (CN) 2010-05-19 EP claimed
WO-1999038833-A1 PROCESS FOR THE HALOGENATION OF ALDEHYDES AND KETONES BROMINE COMPOUNDS LTD. (IL) 1999-08-05 WO claimed
US-4350640-A FROM APPROPRIATE ACID CHLORIDE, WATER-SOLUBLE CYANIDE AND 3-PHENOXYBENZALDEHYDE BAYER AKTIENGESELLSCHAFT (DE) 1982-09-21 US claimed
EP-0058505-A1 Preparation of esters containing an alpha-cyano group in the alcohol portion of the esters FMC Corporation (US) 1982-08-25 EP claimed
US-4323685-A Preparation of esters FMC CORPORATION (US) 1982-04-06 US claimed
US-4322535-A REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE FMC CORPORATION (US) 1982-03-30 US claimed
US-4322534-A Preparation of esters FMC CORPORATION (US) 1982-03-30 US claimed
EP-0046950-A1 Optically active isomers of trans-3(2-(4-chlorophenyl)-vinyl)-2,2-dimethyl-cyclopropion-1-ic acid-(alpha-cyano-4-fluoro-3-phenoxy-benzyl)-esters, process for their preparation and their use as ectoparasiticides BAYER AG (DE) 1982-03-10 EP claimed
EP-0025542-A2 (+/-)-(alpha-cyano-3-phenoxy-4-fluoro-benzylic)esters of (+/-)-trans-3-(E,Z-2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethyl-cyclopropane carboxylic acid, their E and Z isomers, a process for their preparation and their application as ectoparasiticides BAYER AG (DE) 1981-03-25 EP claimed
EP-0024624-A2 4-Fluoro-3-phenoxy-benzaldehyde acetals, process for their preparation and intermediate products therefor BAYER AG (DE) 1981-03-11 EP claimed
EP-0022970-A2 Stereoisomers of alpha-cyano-3-phenoxy-4-fluor-benzyl esters of 2,2-dimethyl-3-(2,2-dichloro-vinyl)-cyclopropane carboxylic acid, process for their preparation and their application as insecticides and acaricides BAYER AG (DE) 1981-01-28 EP claimed
EP-0009792-A1 (4-Fluoro-3-phenoxy-alpha-cyanobenzyl)esters of 3-chlorostyryl-2,2-dimethyl-cyclopropanoic acid, method of preparation and use as ectoparasiticides BAYER AG (DE) 1980-04-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286265-A1 ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL META-HALO PYRETHRATE, A PROCESS FOR PREPARING THE SAME AND THE USES THEREOF CYP8B1, CTRL, CBR3 TTR 1307/4885LMNA 1734/4885GAA 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.