SCHEMBL11032283

SCHEMBL11032283

CC(C)(C)C=Cc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.52
HIF1A Q16665 3/20 0.49
EPAS1 Q99814 1/20 0.49
KDM4E B2RXH2 4/20 0.48
MAPT P10636 4/20 0.48
ALDH1A1 P00352 3/20 0.48
CYP2C9 P11712 3/20 0.48
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA3 P07451 3/20 0.48
CA4 P22748 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
CA5B Q9Y2D0 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2600069 1.00 APP (0.52) APPHIF1AEPAS1KDM4EMAPT
SCHEMBL29484744 0.80 HIF1A (0.53) APPHIF1AEPAS1KDM4EMAPT
SCHEMBL11049215 0.80 CYP3A4 (0.48) APPHIF1AEPAS1KDM4EMAPT
SCHEMBL31474474 0.79 HIF1A (0.47) APPHIF1AEPAS1KDM4EMAPT
SCHEMBL28565142 0.78 ALDH1A1 (0.55) HIF1AEPAS1MAPTALDH1A1CYP2C9
SCHEMBL6693532 0.77 CA12 (0.52) APPHIF1AEPAS1KDM4EMAPT
SCHEMBL31510224 0.76 APP (0.52) APPHIF1AKDM4EMAPTALDH1A1
SCHEMBL31510225 0.76 APP (0.52) APPHIF1AKDM4EMAPTALDH1A1
SCHEMBL2600068 0.76 AHR (0.48) MAPTALDH1A1CYP2C9LMNASMN1; SMN2
SCHEMBL13153164 0.76 NFE2L2 (0.54) APPLMNAALOX5PTGS2NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119827495-A Method for testing alkali purity, alkali strength and alkali residue by using photoetching machine 上海微悦芯材新材料有限责任公司 2025-04-15 CN disclosed
CN-119827496-A Method for testing acid strength and acid production efficiency by using photoetching machine and application 上海微悦芯材新材料有限责任公司 2025-04-15 CN disclosed
CN-115616860-A Deep ultraviolet chemical amplification positive photoresist composition and pattern forming method 北京科华微电子材料有限公司 2023-01-17 CN disclosed
US-20150133493-A1 COUMARIN-BASED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND CANCER MEMORIAL SLOAN KETTERING CANCER CENTER 2015-05-14 US disclosed
US-20110306605-A1 COUMARIN-BASED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND CANCER SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2011-12-15 US disclosed
EP-0057881-B1 AN ANTI-INFLAMMATORY, ANALGESIC, AND ANTIPYRETIC PHARMACEUTICAL COMPOSITION, AND METHOD FOR PRODUCING IT KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-12-04 EP disclosed
US-4035559-A CROSSLINKING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133493-A1 COUMARIN-BASED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND CANCER BACE1, PSEN1, APP APP 3/4885HIF1A 2452/4885EPAS1 2834/4885
US-20110306605-A1 COUMARIN-BASED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND CANCER BACE1, PSEN1, APP APP 3/4885HIF1A 2452/4885EPAS1 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.