SCHEMBL11032473

SCHEMBL11032473

O=C(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
RAPGEF3 O95398 1/20 0.58
KAT6A Q92794 5/20 0.58
LARS1 Q9P2J5 1/20 0.57
F2 P00734 2/20 0.57
PRSS1 P07477 2/20 0.57
PRSS2 P07478 2/20 0.57
PRSS3 P35030 2/20 0.57
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.55
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
NLRP3 Q96P20 1/20 0.53
ATM Q13315 1/20 0.53
CYP19A1 P11511 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774671 0.87 L3MBTL1 (0.61) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL14607535 0.87 L3MBTL1 (0.57) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL29492938 0.86 L3MBTL1 (0.64) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL3267161 0.86 F2 (0.62) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL3267159 0.86 L3MBTL1 (0.59) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL11162145 0.86 L3MBTL1 (0.64) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL7610253 0.84 L3MBTL1 (0.61) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL29644482 0.83 KAT6A (0.73) L3MBTL1KAT6ALMNAALDH1A1SMN1; SMN2
SCHEMBL19630986 0.83 L3MBTL1 (0.65) L3MBTL1RAPGEF3KAT6ALARS1F2
SCHEMBL30549044 0.83 RAPGEF3 (0.60) L3MBTL1RAPGEF3KAT6ALARS1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60210636-A None JP disclosed
JP-S60210636-A NUCLEATING AGENT FOR POLYMER MITSUI PETROCHEM IND LTD 1985-10-23 JP disclosed