Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 9/20 | 0.73 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | FLT1 | P17948 | 1/20 | 0.62 |
| ▸ | FLT4 | P35916 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175525 | 0.88 | KAT6A (0.76) | KAT6ABCL2L1MCL1L3MBTL1LMNA | |
| SCHEMBL9178342 | 0.86 | KAT6A (0.77) | KAT6ABCL2L1MCL1L3MBTL1MEN1 | |
| SCHEMBL7774671 | 0.85 | L3MBTL1 (0.61) | KAT6AL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL20233287 | 0.84 | KAT6A (1.00) | KAT6ALMNASMN1; SMN2 | |
| SCHEMBL9179926 | 0.84 | PTPN1 (0.67) | KAT6ABCL2L1MCL1L3MBTL1LMNA | |
| SCHEMBL11032473 | 0.83 | L3MBTL1 (0.62) | KAT6AL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL174010 | 0.81 | FLT1 (0.77) | KAT6ABCL2L1MCL1L3MBTL1LMNA | |
| SCHEMBL8766875 | 0.81 | NPC1 (0.62) | KAT6ALMNAMEN1KMT2APTPN1 | |
| SCHEMBL3267161 | 0.80 | F2 (0.62) | KAT6AL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3267159 | 0.80 | L3MBTL1 (0.59) | KAT6ABCL2L1MCL1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483501-B | N- (phenylsulfonyl) benzamides and related compounds as BCL-2 inhibitors | 密歇根大学董事会 | 2022-07-01 | — | — | CN | disclosed |