Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909633 | 0.89 | SMN1; SMN2 (0.44) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| SCHEMBL1559916 | 0.89 | ADRB2 (0.39) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| SCHEMBL1558720 | 0.87 | MAPT (0.50) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| Water SCHEMBL6406913 | 0.85 | ADRB2 (0.39) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| SCHEMBL632293 | 0.85 | ADRB1 (0.40) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| SCHEMBL13437541 | 0.84 | BRD4 (0.35) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| SCHEMBL10982611 | 0.83 | BRD4 (0.37) | FOLH1BRD4CREBBPL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11216398 | 0.81 | ADRB2 (0.35) | BRD4CREBBPL3MBTL1MAPTCYP2C9 | |
| SCHEMBL632130 | 0.80 | ADRB2 (0.37) | BRD4CREBBPL3MBTL1MAPTCYP2C9 | |
| SCHEMBL1764304 | 0.77 | MAOA (0.46) | CREBBPMAPTSMN1; SMN2ADRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073505-B1 | BENZO-HETEROCYCLES | BOEHRINGER INGELHEIM KG (DE) | 1985-11-27 | — | — | EP | disclosed |
| US-4460581-A | ANTISPASMODIC AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0073505-A1 | Benzo-heterocycles | BOEHRINGER INGELHEIM KG (DE) | 1983-03-09 | — | — | EP | disclosed |