Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL11032802

NSC1CCCCC1.NSC1CCCCC1.NSC1CCCCC1.c1ccc2scnc2c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 1/20 0.58
TXN P10599 1/20 0.43
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOB P27338 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
CNR1 P21554 1/20 0.33
TSHR P16473 1/20 0.33
DYRK1A Q13627 7/20 0.33
CLK4 Q9HAZ1 5/20 0.33
DYRK2 Q92630 4/20 0.33
DYRK1B Q9Y463 4/20 0.33
DYRK3 O43781 3/20 0.33
CLK1 P49759 3/20 0.33
CLK2 P49760 3/20 0.33
CLK3 P49761 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL9066757 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL5138455 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL677834 0.88 ALDH1A1 (0.61) ALDH1A1HSD17B10TXNHPGDTDP1
Biphenyl SCHEMBL6933950 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL10602275 0.81 ALDH1A1 (0.49) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL28852645 0.81 ALDH1A1 (0.66) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL9066759 0.80 ALDH1A1 (0.51) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL9752175 0.80 ALDH1A1 (0.76) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL11608871 0.80 ALDH1A1 (0.83) ALDH1A1HSD17B10HPGDTDP1CYP1A2
Benzo[D]Thiazole SCHEMBL119610 0.79 ALDH1A1 (0.68) ALDH1A1HSD17B10TDP1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073374-B1 USE OF CYCLIC ACETALS AS A NON-COLOURING PROTECTING AGENT AS REGARDS OZONE BAYER AG (DE) 1986-01-15 EP disclosed