Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL5138455

NSC1CCCCC1.c1ccc2scnc2c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 1/20 0.58
TXN P10599 1/20 0.43
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOB P27338 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
CNR1 P21554 1/20 0.33
TSHR P16473 1/20 0.33
DYRK1A Q13627 7/20 0.33
CLK4 Q9HAZ1 5/20 0.33
DYRK2 Q92630 4/20 0.33
DYRK1B Q9Y463 4/20 0.33
DYRK3 O43781 3/20 0.33
CLK1 P49759 3/20 0.33
CLK2 P49760 3/20 0.33
CLK3 P49761 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL11032802 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL9066757 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL677834 0.88 ALDH1A1 (0.61) ALDH1A1HSD17B10TXNHPGDTDP1
Biphenyl SCHEMBL6933950 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL10602275 0.81 ALDH1A1 (0.49) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL28852645 0.81 ALDH1A1 (0.66) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL9066759 0.80 ALDH1A1 (0.51) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL9752175 0.80 ALDH1A1 (0.76) ALDH1A1HSD17B10TXNHPGDTDP1
Benzo[D]Thiazole SCHEMBL11608871 0.80 ALDH1A1 (0.83) ALDH1A1HSD17B10HPGDTDP1CYP1A2
Benzo[D]Thiazole SCHEMBL119610 0.79 ALDH1A1 (0.68) ALDH1A1HSD17B10TDP1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113619254-A Method for adhering vulcanized shoes and multifunctional treating agent used for method 大东树脂化学股份有限公司 2021-11-09 CN claimed
CN-106459513-B Rubber compound for tyre production comprising silica 株式会社普利司通 2018-06-05 CN claimed
CN-106459513-A Rubber compound for tyre production comprising silica 株式会社普利司通 2017-02-22 CN claimed
CN-105408126-A Process for producing rubber compounds for tyres BRIDGESTONE CORP 2016-03-16 CN claimed
CN-105377576-A Rubber tyre compound production method BRIDGESTONE CORP 2016-03-02 CN claimed
US-5149742-A HEAT CURABLE ADHESIVES BASED ON POLYMERS HAVING A POLYBUTADIENE CHAIN BACKBONE AND CONTAINING HYDROXYL GROUPS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-09-22 US claimed
CN-115348924-A Sulfur-crosslinkable rubber coating mixture 大陆轮胎德国有限公司 2022-11-15 CN disclosed
CN-115348925-A Sulfur-crosslinkable rubber coating mixture 大陆轮胎德国有限公司 2022-11-15 CN disclosed
CN-114806454-A Method for attaching vulcanized shoes 大东树脂化学股份有限公司 2022-07-29 CN disclosed
CN-113619254-A Method for adhering vulcanized shoes and multifunctional treating agent used for method 大东树脂化学股份有限公司 2021-11-09 CN disclosed
CN-113165446-A Puncture and pneumatic vehicle tire 大陆轮胎德国有限公司 2021-07-23 CN disclosed
CN-110997295-A Method for producing a vehicle tyre, vehicle tyre produced according to said method and use of a treated reinforcing support 大陆轮胎德国有限公司 2020-04-10 CN disclosed
CN-106459513-B Rubber compound for tyre production comprising silica 株式会社普利司通 2018-06-05 CN disclosed
US-5149742-A HEAT CURABLE ADHESIVES BASED ON POLYMERS HAVING A POLYBUTADIENE CHAIN BACKBONE AND CONTAINING HYDROXYL GROUPS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-09-22 US disclosed
US-5145905-A Reduced heat evolution HOECHST AG (DE) 1992-09-08 US disclosed
EP-0270073-B1 RUBBER VULCANISATES WITH A REDUCED DEVELOPMENT OF HEAT DURING A DYNAMIC DEFORMATION, PROCESS FOR PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-13 EP disclosed
EP-0197395-B1 REINFORCED RUBBER COMPOSITIONS, PROCESS FOR PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-14 EP disclosed
US-4837266-A BLEND OF TWO RUBBERS AND CURABLE PHENOLIC RESIN HOECHST AG (DE) 1989-06-06 US disclosed
EP-0255632-A1 Rigid, low-damping rubber composition BAYER AG (DE) 1988-02-10 EP disclosed
EP-0197395-A2 Reinforced rubber compositions, process for preparing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-15 EP disclosed