Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 10/20 | 0.32 |
| ▸ | BCHE | P06276 | 7/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028001 | 0.85 | GAA (0.33) | THRATHRB | |
| SCHEMBL10964036 | 0.83 | THRA (0.40) | THRATHRBGPR84ACHEBCHE | |
| SCHEMBL11285365 | 0.83 | HTR2A (0.37) | ACHEBCHE | |
| SCHEMBL11031125 | 0.81 | THRA (0.36) | THRATHRBGPR84ACHEBCHE | |
| SCHEMBL11028290 | 0.79 | S1PR4 (0.36) | THRATHRB | |
| SCHEMBL10495936 | 0.77 | HPGD (0.43) | — | |
| SCHEMBL10963916 | 0.77 | GPR84 (0.36) | THRATHRBGPR84ACHEBCHE | |
| SCHEMBL8656968 | 0.77 | ESRRA (0.43) | GPR84CD44 | |
| SCHEMBL10773706 | 0.76 | NPC1 (0.39) | GPR84ACHEBCHECD44ADRA2A | |
| SCHEMBL8658822 | 0.76 | ALDH1A1 (0.40) | THRBACHECD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |