Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | HRH1 | P35367 | 10/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 7/20 | 0.61 |
| ▸ | DRD5 | P21918 | 6/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | DRD4 | P21917 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145157 | 0.95 | HPGD (0.78) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL11631075 | 0.93 | HPGD (0.81) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL11031853 | 0.91 | HPGD (0.96) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL5004402 | 0.85 | HRH1 (0.70) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL6688657 | 0.84 | HTR1A (0.64) | HPGDSMN1; SMN2DRD2HTR1A | |
| SCHEMBL5249495 | 0.82 | HRH1 (0.66) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL5146718 | 0.82 | HRH1 (0.71) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL5004014 | 0.82 | HRH1 (0.66) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL9236565 | 0.81 | TP53 (0.67) | HPGDSMN1; SMN2HRH1TP53CYP1A2 | |
| SCHEMBL2085565 | 0.81 | HRH1 (0.69) | HPGDSMN1; SMN2HRH1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |
| US-4091114-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4060641-A | ANTIDEPRESSANT | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-11-29 | — | — | US | disclosed |
| US-4024282-A | Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-05-17 | — | — | US | disclosed |