Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | RGS12 | O14924 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724761 | 1.00 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL9201916 | 1.00 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL11723011 | 0.98 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL11724647 | 0.94 | ALDH1A1 (0.80) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL5864233 | 0.94 | SMN1; SMN2 (0.86) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL10632178 | 0.88 | POLB (0.69) | SMN1; SMN2ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL292284 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1TSHRPOLBHSD17B10 | |
| SCHEMBL10353400 | 0.87 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1TSHRPOLBMAPK1 | |
| SCHEMBL17973600 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1TSHRPOLBHSD17B10 | |
| SCHEMBL28350853 | 0.87 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1TSHRPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631333-A | SOLUTION POLYMERIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | claimed |